Background: Influenza virus and other respiratory viruses have been identified as an essential
cause of acute respiratory infections (ARIs) in children worldwide. However, there are few
data on its frequency and clinical presentation in Jordan.
Objectives: We aimed to identify the viral etiology of acute respiratory infections and the various
clinical presentations in hospitalized children, especially those with influenza viruses compared to
other respiratory viruses.
Methods: A retrospective study was conducted at the Jordan University Hospital. All the positive
nasopharyngeal aspirates that were collected from hospitalized children aged 0-19 years from January
2017 to January 2019 were reviewed.
Results: A total of 338 nasopharyngeal aspirates (NPAs) with positive viral serology results were
reviewed. Among the patients younger than four years, the RSV virus was the most frequently detected.
However, the Influenza B virus was the most commonly seen in patients older than 5 years,
H1N1 was more frequent in autumn (29.5%), and RSV was the most frequent virus in winter. Bronchopneumonia
was the most frequent diagnosis among all hospitalized patients, followed by bronchiolitis.
Out of 338 patients, 50.3% had tachypnea, 70.7% of patients were admitted to the pediatric
floor, while 18.6% presented with a severe illness and required admission to the pediatric intensive
care unit (PICU).
Infants under the age of one were more likely to have higher co-infection rates with other viruses
compared to children over five years that had influenza.
Conclusion: Presentations of influenza and other respiratory viruses vary between different age
groups, such as sepsis in children younger than one year.