Generic placeholder image

Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Research Article

Association Between Body Composition and Pulmonary Function Tests Among Health Care Workers in Iran

Author(s): Hamidreza Pouragha, Hosein Kazemi, Gholamreza Pouryaghoub and Ramin Mehrdad*

Volume 17, Issue 1, 2021

Published on: 11 March, 2021

Page: [51 - 58] Pages: 8

DOI: 10.2174/1573398X17666210311143728

Price: $65

Abstract

Background: Why is bodyweight not a predictor of lung function, while height, sex, race, and age are predictors of lung capacity and function? In this study, we want to investigate the association between body composition and pulmonary function. And, as much as possible, answer the question of why bodyweight is not predictive of lung function.

Methods: This cross-sectional study was performed among 2967 employees of Tehran University of Medical Sciences (TUMS) who participated in the TUMS Employees Cohort (TEC) study. The body composition of the participants was measured using the Bioelectrical Impedance Analysis (BIA) method. Anthropometric variables were also measured as a confounder. The pulmonary function of participants was assessed by a forced spirometry test.

Results: The correlation of BIA values including fat-free mass and total body water with a pulmonary function such as FEV1, FVC, and FEF25-75 is higher than most anthropometric values such as weight, wrist circumference, and the waist to hip ratio. Also, in regression analysis, age and sex had an association with pulmonary function, but the weight did not show a significant relationship. On the other hand, fat-free mass and visceral fat were significantly associated with pulmonary function. One is direct and the other is inverse.

Conclusion: We observed a negative association between visceral fat and pulmonary function tests and a direct association between Fat-free mass pulmonary function tests (FEV1 and FVC) adjusted for age, sex, and anthropometric indices.

Keywords: Respiratory function tests, body composition, spirometry, health personnel, COVID-19 pandemic, chronic obstructive pulmonary disease (COPD), fat mass index.

[1]
Forte GC, Almeida JC, da Silva DTR, Hennemann ML, Dalcin PTR. Association between anthropometric markers and asthma control, quality of life and pulmonary function in adults with asthma. J Hum Nutr Diet 2019; 32(1): 80-5.
[http://dx.doi.org/10.1111/jhn.12584] [PMID: 30062748]
[2]
Spinelli A, Pellino G. COVID-19 pandemic: Perspectives on an unfolding crisis. Br J Surg 2020; 107(7): 785-7.
[http://dx.doi.org/10.1002/bjs.11627] [PMID: 32191340]
[3]
Murray CJ, Lopez AD, Organization WH. The global burden of disease: A comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020: summary. World Health Organization 1996.
[4]
Varmaghani M, Dehghani M, Heidari E, Sharifi F, Moghaddam SS, Farzadfar F. Global prevalence of chronic obstructive pulmonary disease: Systematic review and meta-analysis. East Mediterr Health J 2019; 25(1): 47-57.
[http://dx.doi.org/10.26719/emhj.18.014] [PMID: 30919925]
[5]
Varmaghani M, Kebriaeezadeh A, Sharifi F, et al. Death-specific rate due to asthma and chronic obstructive pulmonary disease in Iran. Clin Respir J 2018; 12(6): 2075-83.
[http://dx.doi.org/10.1111/crj.12776] [PMID: 29405628]
[6]
Schünemann HJ, Dorn J, Grant BJ, Winkelstein W Jr, Trevisan M. Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study. Chest 2000; 118(3): 656-64.
[http://dx.doi.org/10.1378/chest.118.3.656] [PMID: 10988186]
[7]
Garcia-Aymerich J, Lange P, Benet M, Schnohr P, Antó JM. Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: A population-based cohort study. Am J Respir Crit Care Med 2007; 175(5): 458-63.
[http://dx.doi.org/10.1164/rccm.200607-896OC] [PMID: 17158282]
[8]
Onofre T, Carlos R, Oliver N, et al. Effects of a physical activity program on cardiorespiratory fitness and pulmonary function in obese women after bariatric surgery: A pilot study. Obes Surg 2017; 27(8): 2026-33.
[PMID: 28386756]
[9]
Crump C, Sundquist J, Winkleby MA, Sundquist K. Interactive effects of physical fitness and body mass index on the risk of hypertension. JAMA Intern Med 2016; 176(2): 210-6.
[PMID: 26784837]
[10]
Finkelstein EA, Khavjou OA, Thompson H, et al. Obesity and severe obesity forecasts through 2030. Am J Prev Med 2012; 42(6): 563-70.
[PMID: 22608371]
[11]
Larsson SC, Bäck M, Rees JMB, Mason AM, Burgess S. Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: A Mendelian randomization study. Eur Heart J 2020; 41(2): 221-6.
[PMID: 31195408]
[12]
Afshin A, Forouzanfar MH, Reitsma MB, et al. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med 2017; 377(1): 13-27.
[PMID: 28604169]
[13]
Rowe A, Hernandez P, Kuhle S, Kirkland S. The association between anthropometric measures and lung function in a population-based study of Canadian adults. Respir Med 2017; 131: 199-204.
[PMID: 28947030]
[14]
Guerra S, Sherrill DL, Bobadilla A, Martinez FD, Barbee RA. The relation of body mass index to asthma, chronic bronchitis, and emphysema. Chest 2002; 122(4): 1256-63.
[PMID: 12377850]
[15]
Chen Y, Rennie D, Cormier YF, Dosman J. Waist circumference is associated with pulmonary function in normal-weight, overweight, and obese subjects. Am J Clin Nutr 2007; 85(1): 35-9.
[PMID: 17209174]
[16]
Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition, and respiratory function in elderly men. Am J Clin Nutr 2005; 82(5): 996-1003.
[PMID: 16280430]
[17]
Santana H, Zoico E, Turcato E, et al. Relation between body composition, fat distribution, and lung function in elderly men. Am J Clin Nutr 2001; 73(4): 827-31.
[PMID: 11273860]
[18]
Mohamed EI, Maiolo C, Iacopino L, Pepe M, Di Daniele N, De Lorenzo A. The impact of body-weight components on forced spirometry in healthy italians. Lung 2002; 180(3): 149-59.
[PMID: 12177729]
[19]
de Oliveira PD, Wehrmeister FC, Horta BL, et al. Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: A cross-sectional analysis nested in a birth cohort. BMC Pulm Med 2017; 17(1): 157.
[PMID: 29179743]
[20]
Oliveira PD, Wehrmeister FC, Pérez-Padilla R, et al. Relationship between body composition and pulmonary function in early adult life: A cross-sectional analysis nested in two birth cohort studies. PLoS One 2016; 11(9): e0163428.
[PMID: 27682232]
[21]
Inomoto A, Fukuda R, Deguchi Phn J, et al. The association between the body composition and lifestyle affecting pulmonary function in Japanese workers. J Phys Ther Sci 2016; 28(10): 2883-9.
[PMID: 27821955]
[22]
Behrens G, Matthews CE, Moore SC, Hollenbeck AR, Leitzmann MF. Body size and physical activity in relation to incidence of chronic obstructive pulmonary disease. CMAJ 2014; 186(12): E457-69.
[PMID: 25002559]
[23]
Nedjat S, Mehrdad R, Yunesian M, Pouragha H, Biagi V, Monazzam-Esmaeelpour MR. Prospective cohort study on the social determinants of health: Tehran University of Medical Sciences employees’ cohort (TEC) study protocol. BMC Public Health 2020; 20(1): 1703.
[PMID: 33187513]
[24]
Kuriyan R. Body composition techniques. Indian J Med Res 2018; 148(5): 648-58.
[PMID: 30666990]
[25]
Khalil SF, Mohktar MS, Ibrahim F. The theory and fundamentals of bioimpedance analysis in clinical status monitoring and diagnosis of diseases. Sensors (Basel) 2014; 14(6): 10895-928.
[PMID: 24949644]
[26]
Culver BH, Graham BL, Coates AL, et al. Recommendations for a standardized pulmonary function report. An official American Thoracic Society technical statement. Am J Respir Crit Care Med 2017; 196(11): 1463-72.
[PMID: 29192835]
[27]
Organization WH. Waist circumference and waist-hip ratio: Report of a WHO expert consultation, Geneva. 2011; 8-11.
[28]
Feng X, Qian Z, Zhang B, et al. number of cigarettes smoked Per Day, smoking index, and intracranial aneurysm rupture: A case- control study. Front Neurol 2018; 9: 380.
[PMID: 29904368]
[29]
Vasheghani-Farahani A, Tahmasbi M, Asheri H, Ashraf H, Nedjat S, Kordi R. The Persian, last 7-day, long form of the international physical activity questionnaire: Translation and validation study. Asian J Sports Med 2011; 2(2): 106-16.
[PMID: 22375226]
[30]
De Lorenzo A, Petrone-De Luca P, Sasso GF, Carbonelli MG, Rossi P, Brancati A. Effects of weight loss on body composition and pulmonary function. Respiration 1999; 66(5): 407-12.
[PMID: 10516536]
[31]
Lim S, Kwon SY, Yoon JW, et al. Association between body composition and pulmonary function in elderly people: The Korean longitudinal study on health and aging. Obesity 2011; 19(3): 631-8.
[PMID: 20706206]
[32]
Janssens J-P. Aging of the respiratory system: Impact on pulmonary function tests and adaptation to exertion. Clin Chest Med 2005; 26(3): 469-84.
[PMID: 16140139]
[33]
Park JE, Chung JH, Lee KH, Shin KC. The effect of body composition on pulmonary function. Tuberc Respir Dis (Seoul) 2012; 72(5): 433-40.
[PMID: 23101008]
[34]
Jung D-H, Shim J-Y, Ahn H-Y, Lee H-R, Lee J-H, Lee Y-J. Relationship of body composition and C-reactive protein with pulmonary function. Respir Med 2010; 104(8): 1197-203.
[PMID: 20299196]
[35]
Eisner MD, Blanc PD, Sidney S, et al. Body composition and functional limitation in COPD. Respir Res 2007; 8(1): 7.
[PMID: 17261190]
[36]
Calella P, Valerio G, Thomas M, et al. Association between body composition and pulmonary function in children and young people with cystic fibrosis. Nutrition 2018; 48: 73-6.
[PMID: 29469024]
[37]
McAuley PA, Artero EG, Sui X, Lee D-c, Church TS, Lavie CJ, Eds. The obesity paradox, cardiorespiratory fitness, and coronary heart disease. Mayo Clinic Proceedings 2012.
[38]
Lee Y-Y, Tsao Y-C, Yang C-K, et al. Association between risk factors of metabolic syndrome with lung function. Eur J Clin Nutr 2020; 74(5): 811-7.
[PMID: 31427761]
[39]
Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006; 116(7): 1784-92.
[PMID: 16823476]
[40]
Rosenkranz SK, Townsend DK, Steffens SE, Harms CA. Effects of a high-fat meal on pulmonary function in healthy subjects. Eur J Appl Physiol 2010; 109(3): 499-506.
[PMID: 20165863]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy