Background: Almost the whole world is observing a pandemic like never before in the
last century, affecting the human lifestyle and economies known as coronavirus disease -2019
(COVID-19). A new severe acute respiratory syndrome that has emerged in China in late 2019 and
spread in more than 210 countries makes a global health care emergency.
Objective: Considering the epidemiological features of COVID-19, it is crucial to prevent the
spread of such a highly infectious disease through effective control methods such as early detection,
isolation, and treatment strategies.
Conclusion: This review highlights the SARS-CoV-2 transmission routes among communities and
control measures, improving the quarantine and isolation of infected individuals. The “gold standard”
molecular and other rapid diagnostic tests used to detect SARS-CoV-2 with their benefits
and limitations have been reported. Several repurposed drugs, including antivirals trailed for
COVID-19 patients, and supportive treatments, such as general, cellular, and immune therapies
with the role of vitamins in the safe deployment for COVID-19 patients, have been discussed. Finally,
the review also encompasses an overview and update about the recent development of
COVID-19 vaccines and ongoing clinical studies, providing further research advances.