Recent Advances in the Transition Metal-Catalyzed Addition of Carboxylic Acids to Alkynes

(E-pub Ahead of Print)

Author(s): Victorio Cadierno*

Journal Name: Current Organic Chemistry

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Recent advances in the metal-catalyzed hydrofunctionalization of alkynes with carboxylic acids are comprehensively reviewed. Both inter- and intramolecular processes, leading respectively to enol esters and lactones, are discussed, as well as the involvement of these transformations in the synthesis of natural products and biologically active molecules, and the assembly of elaborated heterocyclic compounds though cascade processes. Literature published since 2011 is covered.

Keywords: Enol esters, lactones, alkynes, hydro-oxycarbonylation reactions, cycloisomerization reactions, metal-catalyzed transformations

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Article Details

Published on: 07 March, 2021
(E-pub Ahead of Print)
DOI: 10.2174/1385272825666210308113837
Price: $95

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