Role of Pulmonary Ultrasound in COVID-19 Pandemics

Author(s): Daniil Starostin*, Artem Kuzovlev

Journal Name: Current Respiratory Medicine Reviews

Volume 17 , Issue 1 , 2021

Become EABM
Become Reviewer
Call for Editor

Graphical Abstract:


Currently, there is a lot of clinical data on the basics of lung ultrasound (US) examination in patients with COVID-19. This article is focused on the principles of pneumonia diagnosis. It is established that the use of ultrasound can be informative at the prehospital stage and triage of patients and also detection of mild forms of the course of the disease.

Keywords: Coronavirus, COVID-19, lung ultrasound, pneumonia, type II alveolar cells (AT2), X-rays.

Temporary guidelines Prevention, diagnosis and treatment of new coronavirus infection (COVID-19). Version No 6 of 04/28/2020 2020. Available from:
World Health Organization Coronavirus disease 2019 (COVID-19) Situation Report 2020. Available from:
World Health Organization Infection prevention and control during health care when COVID-19 is suspected Interim guidance 2020. Available from:
Ong SWX, Tan YK, Chia PY, et al. Air, surface, environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA 2020; 323(16): 1610-2.
Yoon SH, Lee KH, Kim JY, et al. Chest radiographic and CT findings of the 2019 novel coronavirus disease (COVID-19): analysis of nine patients treated in Korea. Korean J Radiol 2020; 21: 494-500.
Jin YH, Cai L, Cheng ZS, et al. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus. Mil Med Res 2020; 7(1): 4.
Fang Y, Zhang H, Xie J, et al. Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology 2020; 296(2): E115-7.
Peng Q, Wang X, Zhang L. Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic. Intensive Care Med 2020; 1: 2.
Soldati G, Smargiassi A, Inchingolo R, et al. Is there a role for lung ultrasound during the COVID-19 pandemic? J Ultrasound Med 2020; 10: 1002.
Pereira E Jr, Bethlem M, Vieira A, et al. Lung ultrasound in COVID-19 pandemic. Should be used for diagnosis and monitoring from now on? Winfocus 2020; 1: 1-3.
Buonsenso D, Pata D, Chiaretti A. COVID-19 outbreak: less stethoscope, more ultrasound. Lancet Respir Med 2020; 8(5): 27.
Huang Y, Wang S, Liu Y, et al. A preliminary study on the ultrasonic manifestations of peripulmonary lesions of non-critical novel coronavirus pneumonia (COVID-19) SSRN 2020; 1: 14.
Buonsenso D, Piano A, Raffaelli F, et al. Point of care lung ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak. Eur Rev Med Pharmacol Sci 2020; 24(5): 2776-80.
Poggiali E, Dacrema A, Bastoni D, et al. Can Lung US Help Critical Care Clinicians in the Early Diagnosis of Novel Coronavirus (COVID-19) Pneumonia? Radiology 2020; 295(3): E6.
Mojoli F, Bouhemad B, Mongodi S, et al. Lung ultrasound for critically ill patients. Am J Respir Crit Care Med 2019; 199: 701-14.
Mayo PH, Copetti R, Feller-Kopman D, et al. Thoracic ultrasonography: a narrative review. Intensive Care Med 2019; 45: 1200-11.
Soldati G, Demi M, Smargiassi A, et al. The role of ultrasound lung artifacts in the diagnosis of respiratory diseases. Expert Rev Respir Med 2019; 13: 163-72.
Soldati G, Smargiassi A, Mariani AA, et al. Novel aspects in diagnostic approach to respiratory patients: is it the time for a new semiotics? Multidiscip Respir Med 2017; 12: 15.
Demi M, Prediletto R, Soldati G, et al. Physical mechanisms providing clinical information from ultrasound lung images: hypotheses and early confirmations. IEEE Trans Ultrason Ferroelectr Freq Control 2020; 67: 612-23.
Demi L, van Hoeve W, van Sloun RJG, et al. Determination of a potential quantitative measure of the state of the lung using lung ultrasound spectroscopy. Sci Rep 2017; 7: 12746.
Soldati G, Demi M, Inchingolo R, et al. On the physical basis of pulmonary sonographic interstitial syndrome. J Ultrasound Med 2016; 35: 2075-86.
Soldati G, Smargiassi A, Inchingolo R, et al. Lung ultrasonography and vertical artifacts: the shape of air. Respiration 2015; 90: 86.
Soldati G, Smargiassi A, Inchingolo R, et al. Lung ultrasonography may provide an indirect estimation of lung porosity and airspace geometry. Respiration 2014; 88: 458-68.
Lichtenstein DA. Lung ultrasound in the critically ill. Ann Intensive Care 2014; 4(1): 1.
Wuzhu L, Shushan Z, Binghui C, et al. A clinical study of noninvasive assessment of lung lesions in patients with Coronavirus Disease-19 (COVID-19) by Bedside Ultrasound. Ultraschall Med 2020; 1: 1-15.
Xiong T-Y, Redwood S, Prendergast B, et al. Coronaviruses and the cardiovascular system: acute and long-term implications. European Heart J 2020; 41(19): 1798-800.
Hendren NS, Drazner MH, Bozkurt B, et al. Description and proposed management of the acute COVID-19 cardiovascular syndrome. circulation 2020; 141(23): 1903-14.
Via G, Hussain A, Wells M, et al. International evidence-based recommendations for focused cardiac ultrasound. J Am Soc Echocardiogr 2014; 27(7): 683.e3.
Clinical recommendations. Community-acquired pneumonia. 2018. Available from: federalnye-klinicheskie-rekomendatsii/
Lichtenstein D, Mezi re G. Relevance of lung ultrasound in the diagnosis of acute respiratory failure. Chest 2008; 134: 117-25.
Soummer A, Perbet S, Brisson H, et al. Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress. Crit Care Med 2012; 40(7): 2064-72.
Bouhemad B, Brisson H, Le-Guen M, et al. Bedside ultrasound assessment of positive end expiratory pressure-induced lung recruitment. Am J Respir Crit Care Med 2011; 183: 341-7.
Pan F, Ye T, Sun P, et al. Time course of lung changes of chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia.Radiology 2019; 295: 3.
Yuhui W, Chengjun D, Yue H, et al. Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study. Radiology 2020; 1: 1-21.
Safonov DV, Shakhov BE. Ultrasound diagnosis of inflammatory pulmonary disease: a training manual. M Vidar 2011; 120.
Volpicelli G, Elbarbary M, Blaivas M, et al. International evidence-based recommendations for point-of-care lung ultrasound. Intensive Care Med 2012; 38(4): 577-91.
Lichtenstein DA. Lung ultrasound in the critically ill. In: The BLUE Protocol Springer. 2016; 1: p. 376.
Sign A, Mei X, Huang M, et al. Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of Infection. Radiology 2020; 20: 200463.
Muller T, Martiny H, Merz E, et al. DEGUM Recommendations on infection prevention in ultrasound and endoscopic ultrasound. Ultraschall Med 2018; 39: 284-303.
ACEP. American College of Emergency Physicians Guideline for Ultrasound Transducer Cleaning and Disinfection Ann Emerg Med 2018; 72(4): 45-7.
Nyhsen CM, Humphreys H, Koerner RJ, et al. Infection prevention and control in ultrasound best practice recommendations from the European Society of radiology Ultrasound Working Group. Insights Imaging 2017; 8(6): 523-35.
Abramowicz JS, Evans DH, Fowlkes JB, et al. Guidelines for cleaning transvaginal ultrasound transducers between patients ultrasound. Med Biol 2017; 43: 1076-9.
Basseal J, Westerway S, Juraja M, et al. Guidelines for reprocessing ultrasound transducers. Australas J Ultrasound Med 2017; 20: 30-40.
CDC Center for disease control interim infection prevention and control recommendations for patients with suspected or confirmed Coronavirus Disease 2019 (COVID-19) in Healthcare Settings. 2020. Available from:
Guidance on preparing workplaces for COVID-19 United States department of labor occupational safety and health administration. 2020. Available from:
Skowronek P, Wojciechowski A, Leszczynski P, et al. Can diagnostic ultrasound scanners be a potential vector of opportunistic bacterial infection? Med Ultrason 2016; 18: 326-31.
Abramowicz JS, Basseal J. WFUMB position statement: how to safely conduct ultrasound and disinfect ultrasound equipment under the conditions of COVID-19 (translation into Russian). Ultrasound Funct Diagnost 2020; 1: 12-23.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2021
Published on: 01 March, 2021
Page: [3 - 7]
Pages: 5
DOI: 10.2174/1573398X17666210301122718
Price: $65

Article Metrics

PDF: 157