The current SARS coronavirus-2 (SARS-CoV-2) pandemic has raised serious concerns
regarding the inefficiency of available diagnostic methods for rapid and efficient detection of the
disease. It is agreed widely that Real-time Polymerase Chain Reaction (RT-PCR) and antibody-
based assays have several limitations that did not help much in preventing the exponential
spread of the disease in a short span of period. Unarguably, the world needs “new-generation diagnostic
intervention(s)” against rapidly spreading disease like SARS-CoV-2. We have presented an
aptamer-based strategy as a possible point of care testing for the diagnosis of the disease. It has several
advantages over current tools available and can be used for efficient combating by the mean of
quick,cost-effective and much more accurate diagnostic against the enigmatic SARS-CoV-2 disease
and similar pandemic which world may possibly encounter in the future.
Keywords: SARS-CoV-2, RT-PCR, diagnosis, point of care testing, aptamer, ELONA.
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