Complextation of Oppositely Charged Polymer: Novel Approaches for Drug Delivery

Author(s): Ritesh Kumar Tiwari*, Lalit Singh, Vaibhav Rastogi

Journal Name: Current Drug Delivery

Volume 18 , Issue 8 , 2021


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Abstract:

The polyelectrolyte complexes (PECs) are adaptable constructs shaped by electrostatic interaction between biopolymers with inverse charges. Polyelectrolyte edifices comprise an exceptional class of polymeric mixtures comprising of polyions with inverse charges, which can be charged either cationically or anionically. Significant advancement has been made in the course of recent years towards new medication conveyance frameworks. The subject of broad, essential and applied exploration covers the marvel of interpolymer collaborations and polyelectrolyte complex development. Basically, applied polyelectrolytes raise on the grounds that the advantages of supportability are perceived in the scholarly world and modern examination settings. Polyelectrolytes are a form of polymer that has endless ionizable practical arrangements. Ionized polyelectrolytes in the arrangement can form a complex with an oppositely charged particle called a polyelectrolyte complex. The review article emphasizes on PECs and their classification, characterization, as well as a critical analysis of the current research and applicability in the drug delivery technology.

Keywords: Polyelectrolyte complex, polymer, drug delivery, polyions, polycation, Application.

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Article Details

VOLUME: 18
ISSUE: 8
Year: 2021
Published on: 10 February, 2021
Page: [1073 - 1081]
Pages: 9
DOI: 10.2174/1567201818666210211094727
Price: $95

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