TRIM65 in White Matter Lesions, Innate Immunity, and Tumor

(E-pub Ahead of Print)

Author(s): Bingxue Liu, Yunlian Tang*, Ping Yang, Chu Wu, Yue Huang

Journal Name: Current Molecular Pharmacology


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Abstract:

Most of the tripartite motif (TRIM) family proteins have E3 ubiquitin ligase activities and also have a variety of functions in cellular processes such as intracellular signal transduction, apoptosis, innate immunity and carcinogenesis. TRIM65 is a member of the TRIM family. More and more evidences have shown a unique and importance of TRIM65 protein in the occurrence and development of some diseases. In this review, the importance on TRIM65 in white matter lesions, innate immunity and the effect of tumors was mainly reviewed.

Keywords: TRIM65, white matter lesions, innate immunity, carcinogenesis, E3 ubiquitin ligase, tumor

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Article Details

Published on: 03 February, 2021
(E-pub Ahead of Print)
DOI: 10.2174/1874467214666210203211603
Price: $95

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