Background: The safety and quality of food have been a matter of great discussion
throughout the centuries and the application of nanotechnology in the field of nutraceuticals i.e.
nanoceuticals has improved the variety and protection of food products in many ways.
Objective: Improving the quality and safety of food products with a view to improving public
health and the invasion of nanotechnological advancements in the area of nutrition have resulted in
the expansion of novel foods with improved oral bioavailability as well as thermal stability. The
main objective of this review is to summarize the available literature on nanoceuticals including patents
and clinical trials.
Methods: The review was extracted from the searches performed on PubMed, Google Patents and
Google Scholars, etc. Data from these searches were collected and evaluated for getting the information
about the available literature on the nanoceuticals. Along with this, some reported patents
have also been included in this review in order to conclude the future of nanoceuticals.
Results: The literature so obtained was studied thoroughly as per the requirement of the objective
of this review. The details of nanoceuticals including major applications, regulatory aspects, some
reported patents and clinical trials are compiled here in this review. Nanoceuticals like vitamins,
antibiotics, bioactive peptides, probiotics, etc., which are dispersed, absorbed or incorporated in
nano diameter range sacs, have improved solubility, delivery properties, biological activities, protection
against degradation and therefore have improved biological activities and delivery to the target
cells and tissues in the body. Different regulations from various countries recommend that any
food ingredients which result from the use of nanotechnologies must undergo safety risk assessment
standards before entering into the market as nano-food.
Conclusion: The idea of “nanoceuticals” is increasing enthusiasm and marketable dairy/food and
food supplements. This article focuses on the history, applications, regulation aspects, patents, clinical
trials and future prospects of nanoceuticals.