Parkinson’s disease (PD) is a progressive neurodegenerative disorder that exerts a huge burden on
our society. The occurrence of this neurodegenerative disease has been increasing day-by-day. PD can be a serious
concern if the patients are left untreated. However, conventional treatment has many side-effects and less
bioavailability in the brain. Therefore, the necessary measurement is required to solve the limitations of PD
treatment. Nanotechnology has made a major contribution to comprehend PD pathogenesis. Nanotechnology
can provide efficient therapies that have reduced side-effects and increased bioavailability in the brain. This review
emphasizes the emerging promise of nanoparticle-based treatment, drug delivery, and other therapeutic approaches
for PD. Besides, the advantages of different approaches on nanotechnology platforms are far better
over conventional therapy in the treatment of PD.
Keywords: Parkinson's disease, progressive neurodegenerative disorder, nanotechnology, nanoparticles, α-synuclein, blood-brain barrier.
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