Neurodegenerative diseases like Alzheimer's disease, Parkinson's disease, Huntington’s disease, Multiple
Sclerosis and Ischemic stroke have become a major health problem worldwide. Pre-clinical studies have demonstrated the
beneficial effects of flavonoids on neurodegenerative diseases and suggesting them to be used as therapeutic agents.
Kaempferol is found in many plants such as tea, beans, broccoli,strawberriesand has neuroprotective effects against the
development of many neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease and Huntington's disease.
The present study summarizesthe neuroprotective effects of kaempferol in various models of neurodegenerative diseases.
Kaempferol delays the initiation as well as the progression of neurodegenerative disorders by acting as a scavenger of free
radicals and preserving the activity of various antioxidant enzymes. Kaempferolcan crossthe blood-brain barrier (BBB), and
therefore results inan enhanced protective effect. The multi-target property of kaempferol makes it a potential dietary
supplement in preventing and treating neurodegenerative diseases.