Natural Flavans and (Iso)Flavanones with Anticancer Activity: A Review

Author(s): Arindam Gangopadhyay*

Journal Name: Current Organic Chemistry

Volume 25 , Issue 9 , 2021

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Graphical Abstract:


The present review describes 108 new examples of naturally occurring flavans and flavanones having cytotoxic potential, which have been reported during the period of 2005 to mid-2020. These compounds are found either as aglycones or as glycosides, comprising flavans, flavanones, isoflavanones and miscellaneous flavanones (homo- and bi-flavanones). The main topics addressed in this review are source, structure, and cytotoxic activity in detail and the structure-activity relationship.

Keywords: Natural flavans and flavanones, cytotoxicity, anticancer activity, aglycones, glycosides, structure-activity relationship.

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Article Details

Year: 2021
Published on: 25 May, 2021
Page: [1028 - 1046]
Pages: 19
DOI: 10.2174/1385272825666210126095118
Price: $58

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PDF: 19