A simple, efficient and green protocol has been developed for the synthesis of polysubstituted dihydropyridines
via one-pot, four-component reaction of aldehydes, arylamines, dialkyl acetylenedicarboxylate, and malononitrile. The reaction was proceeded at room temperature in the absence of catalyst in aqueous ethyl lactate under visible light irradiation.
The main advantages of the present approach are mild reaction condition, high yield, no column chromatography, clean
reaction profile, environmentally friendly and sustainable from the economic point of view.