Biologically Active Natural Products from Asia and Africa: A Selection of Topics

Biologically Active Natural Products from Asia and Africa: A Selection of Topics

Both Asia and Africa are home to many plants that can be used for the treatment of many diseases and their medicinal properties are gaining interest in western societies. Medicinal plants from Asia ...
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Ethnobotanic, Phytochemical, and Biological Activities of Aristolochia longa L.: A Review

Pp. 84-105 (22)

Amina El Yahyaoui El Idrissi, Aya Khouchlaa, Abdelhakim Bouyahya, Mereym El Fessikh, Youssef Bakri and M`hamed Tijane

Abstract

Aristolochia longa is a medicinal plant used in traditional Mediterranean pharmacopeia to treat different diseases. It shows significant anti-inflammatory, antidiabetic, antioxidant, antibacterial, and antitumoral pharmacological effects. The extracts of this plant are rich in bioactive molecules belonging to different chemical families such as limonene, aristolochic acid, β-caryophyllene, and deenax. However, excessive use of this plant causes severe toxicity to the user. The aim of the present review is to give particular emphasis on the most recent findings on biological effects of the major groups of Aristolochia longa components, their therapeutic use, and the active ingredient responsible for the toxicity of this plant, which constitutes a public health problem observed with it’s wide use in cancer patients.

Keywords:

Aristolochia longa, Anticancer, Antibacterial, Anti-inflammatory, Phytochemical, Toxicity.

Affiliation:

Department of Biology, Faculty of Science, Genomic Center of Human Pathologies, Faculty of Medicine, Laboratory of Human Pathologies Biology, Mohammed V University, Rabat, Morocco.