A Comprehensive Review on Recently Detected Herbal Phytoactives Having Anti-Diabetic Potential for Various Diabetes-Related Complications

(E-pub Ahead of Print)

Author(s): Pranay Wal*, Ankita Wal, Rashmi Saxena Pal, Priya Singh

Journal Name: Current Traditional Medicine


Article ID: e130121190300
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Abstract:

Background: Diabetes is a metabolic, endocrine disorder which is featured by hyperglycemia and glucose intolerance, primarily due to beta cell destruction, with Insulin Resistance playing a secondary role. It is treated with the help of many chemical based drugs as well as natural derivatives.

Objective: There is urgent need to develop new efficacious, cheaper and more available drugs to face this growing public health challenge. Many anti-diabetic drugs are often often associated with many adverse effects.

Materials & Methods: Literature was reviewed in a narrative manner in order to pertain the information about active phytoactives present in the different plants. Anti-diabetic drugs are often loaded with side effects; therefore, review is being done for the selection of effective natural therapeutic moieties with less or no adverse effects.

Results: In this review article, we described the detailed review of recently detected bioactive compounds present in different natural substances; which can be used effectively for diabetes related adversities.

Conclusion: Natural products based bioactive molecules have been proven to improve insulin resistance and other related complications through suppression of inflammatory signaling pathways.

Keywords: diabetes, insulin, herbal, phytoactives, potential, natural

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Article Details

Article ID: e130121190300
Published on: 13 January, 2021
(E-pub Ahead of Print)
DOI: 10.2174/2215083807666210114114334
Price: $95

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