Microwave-assisted Claisen Rearrangement of 1-Allyloxy-4-hydroxybenzene in the Presence of Metal Salt

Title:Microwave-assisted Claisen Rearrangement of 1-Allyloxy-4-hydroxybenzene in the Presence of Metal Salt

Volume: 8 Issue: 1

Author(s): Fumiyoshi Ozaki and Yutaka Okada*

Affiliation:

• Department of Applied Chemistry, Ritsumeikan University, Kusatsu,Japan

Keywords: Microwave irradiation effect, Claisen rearrangement, metal salt, allylarenes, electron density, ethereal oxygen, phenoxide ion.

Abstract: Microwave-assisted Claisen rearrangement of allyloxybenzene with a hydroxyl group was conducted in the presence of metal salts. The rearrangement was promoted in the presence of an alkali metal salt, because the reaction substrate was converted into a phenoxide-type ion, which can efficiently absorb microwaves. In contrast, a Lewis acid was strongly coordinated to the ethereal oxygen, and this structure could also absorb microwaves efficiently.

Cite this article as:

Ozaki Fumiyoshi and Okada Yutaka *, Microwave-assisted Claisen Rearrangement of 1-Allyloxy-4-hydroxybenzene in the Presence of Metal Salt, Current Microwave Chemistry 2021; 8 (1) . https://dx.doi.org/10.2174/2213335607666210106094449