Background: SARS-COV-2 causes a highly pathogenic disease called COVID-19. This
disease leads to a variety of respiratory infections like pneumonia, cold, sneezing, etc. As this disease
is being transmitted via airborne droplets, it is highly essential to use PPEs, including masks,
gloves, etc. This virus interacts with the ACE2 receptor and further makes its entry into host cells
leading to viral pathogenesis. This viral is reported to be originated from the Wuhan market, China.
Despite on-going efforts to control the spread, a number of cases of COVID-19 are increasing on a
Objective: This study aims to collect more information about aspects of nanotechnology-based applications
towards COVID-19 management.
Methods: A systemic search has been carried out using PubMed, Google Scholar, CNKI, etc., for
Results and Conclusion: Nanotechnology-based various approaches like nanomedicines, surface
coatings with nanoparticles, nanoparticle coated PPEs, and nanosensors could significantly reduce
the healthcare burden by reducing the spread. The current review focuses on various approaches of
nanotechnology during the pandemic COVID-19.