Background: The present study outlines the green synthesis of copper oxide (GS-CuO) nanoparticles using
Magnolia champaca plant floral extract for the first time. Computational analysis showed the role of GS-CuO
nanoparticles on cardiac enzymes ACE2 and SOD1 functional expression through hydrogen bond interaction with amino
Method: The synthesized GS-CuO nanoparticles were characterized by various techniques like X-Ray Diffraction, UVVis Spectrophotometer, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy and Transmission
Results: Nanoparticles demonstrate the presence of spherical shape and size 20 nm. The particles have many active sites
and as compared to the bulk materials, and thus, the computational analysis was conducted against angiotensin-converting
enzyme and superoxide dismutase to visualize the cardioprotective effects.
Conclusion: The in-silico approach established valuable information on cardioprotective effects of green synthesized
oxide nanoparticles using Magnolia champaca.