Abstract
Coronavirus disease-2019, a viral disease caused by the novel severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), was identified by the Centre for Disease Control (CDC), China, on January 7, 2020. This mysterious respiratory epidemic occurred in Wuhan, China, in late December 2019. A month after its outbreak in China, the World Health Organization (WHO) declared it as a public health emergency of international concern (PHEIC) due to its severity and high transmission potential throughout the world, leading many nations to implement multiple lockdown sessions and strict social distancing measures. As of September 21, 2020, 30,675,675 active cases and 954,417 deaths had been reported worldwide. Intensive research is being carried out across the globe to identify precise diagnostic techniques and develop novel, effective vaccines against the virus. Herein, we elaborate on details of epidemiology, genetics, pathophysiology, diagnosis, prevention, and vaccine trials related to this pandemic.
Keywords: COVID-19, global outbreak, novel coronavirus, pathogenesis, SARS-CoV-2, vaccines.
Coronaviruses
Title:2019 Novel Coronavirus: A Review on Epidemiology, Pathophysiology, Diagnosis and Current Clinical Trials in Vaccine Development
Volume: 2 Issue: 8
Author(s): Megala Jayaraman*, Sabari Krishna B. B., Parijat Dutta, Jayesh Telang, Sreshta Adhikari and Arpan Neeraj Pardeshi
Affiliation:
- Department of Genetic Engineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur-603203, Chennai, Tamil Nadu,India
Keywords: COVID-19, global outbreak, novel coronavirus, pathogenesis, SARS-CoV-2, vaccines.
Abstract: Coronavirus disease-2019, a viral disease caused by the novel severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), was identified by the Centre for Disease Control (CDC), China, on January 7, 2020. This mysterious respiratory epidemic occurred in Wuhan, China, in late December 2019. A month after its outbreak in China, the World Health Organization (WHO) declared it as a public health emergency of international concern (PHEIC) due to its severity and high transmission potential throughout the world, leading many nations to implement multiple lockdown sessions and strict social distancing measures. As of September 21, 2020, 30,675,675 active cases and 954,417 deaths had been reported worldwide. Intensive research is being carried out across the globe to identify precise diagnostic techniques and develop novel, effective vaccines against the virus. Herein, we elaborate on details of epidemiology, genetics, pathophysiology, diagnosis, prevention, and vaccine trials related to this pandemic.
Export Options
About this article
Cite this article as:
Jayaraman Megala *, B. B. Krishna Sabari , Dutta Parijat , Telang Jayesh , Adhikari Sreshta and Pardeshi Neeraj Arpan , 2019 Novel Coronavirus: A Review on Epidemiology, Pathophysiology, Diagnosis and Current Clinical Trials in Vaccine Development, Coronaviruses 2021; 2 (8) : e260721189629 . https://dx.doi.org/10.2174/2666796701666201230104321
DOI https://dx.doi.org/10.2174/2666796701666201230104321 |
Print ISSN 2666-7967 |
Publisher Name Bentham Science Publisher |
Online ISSN 2666-7975 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Design, Synthesis and Antiplasmodial Evaluation of Sulfoximine-triazole Hybrids as Potential Antimalarial Prototypes
Medicinal Chemistry Human Skeletal Muscle Aging and the Oxidative System: Cellular Events
Current Aging Science An Update on the Xenograft and Mouse Models Suitable for Investigating New Therapeutic Compounds for the Treatment of B-Cell Malignancies
Current Pharmaceutical Design Allosteric Enhancers of A1 Adenosine Receptors: State of the Art and New Horizons for Drug Development
Current Medicinal Chemistry Addressing the Importance of Stem Cell-Based Therapy: A Perspective in the Treatment of COVID-19
Current Molecular Medicine Recent Advances in the Structure-Based Design of Neuraminidase Inhibitors as Antiinfluenza Agents
Current Medicinal Chemistry Synthesis and Anti-cancer Activities of Apigenin Derivatives
Medicinal Chemistry Characteristic Peptides of Protein Secondary Structural Motifs
Protein & Peptide Letters Microwave-Assisted, Solid-Phase Synthesis of a Chiral 1,2,3,4-Tetrahydroquinoline Library
Combinatorial Chemistry & High Throughput Screening Study of the Relationships between COVID-19, Associated Diseases, and Vitamins
Coronaviruses From Nucleic Acids to Drug Discovery: Nucleobases as Emerging Templates for Drug Candidates
Current Medicinal Chemistry The Present Utility and Future Potential for Medicinal Chemistry of QSAR / QSPR with Whole Molecule Descriptors
Current Topics in Medicinal Chemistry The Challenges of Biomedical Waste Management During the Ongoing Coronavirus Disease-19 (COVID-19) Pandemic: The Current Scenario
Micro and Nanosystems Graphical Abstracts
Letters in Drug Design & Discovery Acknowledgements to Reviewers
Letters in Drug Design & Discovery The Bioisosteric Concept Applied to Cannabinoid Ligands
Current Medicinal Chemistry Synthesis, Characterisation, Anti-Microbial Activity and Docking Studies of Novel Dispiro- Oxindolopyrrolidines
Current Chemical Biology Diffuse Alveolar Hemorrhage, A Potentially Life-Threatening Manifestation in Systemic Lupus Erythematosus and the Antiphospholipid Syndrome
Current Respiratory Medicine Reviews Development of DNA Topoisomerase II-Mediated Anticancer Agents, 3-(9- Acridinylamino)-5-hydroxymethylanilines (AHMAs) and Related Compounds
Current Medicinal Chemistry Black Fungus: An Alarming Infection During Novel Coronavirus: A Review
Anti-Infective Agents