2019 Novel Coronavirus: A Review on Epidemiology, Pathophysiology, Diagnosis and Current Clinical Trials in Vaccine Development

(E-pub Ahead of Print)

Author(s): Megala Jayaraman*, Sabari Krishna B. B., Parijat Dutta, Jayesh Telang, Sreshta Adhikari, Arpan Neeraj Pardeshi

Journal Name: Coronaviruses
The World's First International Journal Dedicated to Coronaviruses

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Coronavirus disease-2019, a viral disease caused by a novel severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) was identified by the Centre for Disease Control (CDC), China on January 7, 2020. This mysterious respiratory epidemic occurred in Wuhan, China, in late December 2019. A month later its outbreak in China, the World Health Organization (WHO) declared it as a public health emergency of international concern (PHEIC) due to its severity and high transmission potential throughout the world, leading many nations to implement multiple lockdown sessions and strict social distancing measures. As of September 21, 2020, 30,675,675 active cases and 954,417 deaths had been reported worldwide. Intensive research is being carried out across the globe to identify precise diagnostic techniques and to develop novel, effective vaccines against the virus. Herein, we elaborate on details of epidemiology, genetics, pathophysiology, diagnosis, prevention, and vaccine trials related to this pandemic.

Keywords: COVID-19, global outbreak, novel Coronavirus, pathogenesis, SARS-CoV-2, vaccines

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(E-pub Ahead of Print)
DOI: 10.2174/2666796701666201230104321

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