Background: Ovarian granulosa cell tumors that originate from the sex cord-stromal cells represent 2% to 5%
of all ovarian cancers. These tumors constitute two subgroups according to their clinical and histopathological features:
juvenile granulosa cell tumors (JGCT) and adult granulosa cell tumors (AGCT). Granulosa cell tumor (GCT) is
considered to be a low-grade malignancy with a favorable prognosis.
Methods: This case series includes four patients who admitted to our university hospital and had an MRI examination
within 5 years.
Results: The histopathological subtype of granulosa tumor was the adult type in 3 patients and juvenile type in 1 patient.
Even though its extremely rare, bone metastases were present in one of our patients. Liver metastases were also detected
in one patient. The MRI examination of tumors revealed a heterogeneous solid mass that contained cystic components in 3
patients. In one of our patients, the tumor had a multiseptated cystic feature, and all of the tumors were ovoid or round
with smooth margins. T1 signal hyperintensity, not suppressed on fat saturation sequences, observed in our 3 patients,
which represents its hemorrhagic content.
Conclusion: Even though granulosa cell tumor shows a wide spectrum in terms of tumor appearance, some common
findings have been shown and especially a hemorrhagic content could be a clue for us. The tumor is known to have a good
prognosis, but it may have an unpredictable clinical course, so close follow-up has a great importance.