Background: Despite the availability of many topical formulations for scar treatment, an objective evaluation of
their effect is lacking.
Objective: To assess the physiological, structural, and mechanical parameters of scar healing by a scar ointment (MEBOScar).
Methods: 45 patients from the Department of Obstetrics at Al Ain Hospital, UAE, with recently acquired Pfannenstiel scars
were recruited into this prospective, open-label, controlled study. Scar ointment was applied to a lateral third of the scar;
positive control (silicone gel based topical) to the other lateral third; the middle third was left untreated (negative control).
The scars were evaluated at 4 time points up to 12 weeks using non-invasive devices and a scar questionnaire.
Results: In comparison with silicone gel, there was a significant reduction in trans epithelial water loss at weeks 2,4,8, and
12 (p<0.001) and scar area at weeks 4, 8 and 12 (p<0.001) with scar ointment. The skin elasticity at week 4 was significantly
increased by scar ointment (p=0.007). By week 12, gross colour mismatch of the scar was described by 9% patients with
scar ointment (24% with silicone gel, 42% with no treatment; p<0.001). There was significant improvement in scar texture
with scar ointment by week 12 (p<0.001).
Conclusions: Scar ointment has beneficial effects on objective and subjective patient-reported parameters of Pfannenstiel