Multicomponent Reaction (MCR)
Pp. 176-196 (21)
Marcus Vinícius Nora de Souza
Multicomponent reaction (MCR) is a type of reaction based on a mixture of
three or more compounds or reagents leading only to one or a major molecule being
able to form complex molecules with a high degree of control of the stereogenic
centers in only one step. This methodology is also a useful tool in medicinal chemistry
to produce a diversity of compounds for biological evaluation. Due to its importance,
the exercises below focus on this technique.
Bioactive compounds, Chemical transformations, Combinatorial
chemistry, Drugs, Exercises, Heteroaromatic compounds, Medicinal chemistry,
Molecules, Multicomponent reaction (MCR), Reaction conditions, Reagents,
Retrosynthetic analysis, Substances, Synthesis, Synthons.
FioCruz-Fundação Oswaldo Cruz Rio de Janeiro - RJ, 21040-900, Brazil.