Exercises in Organic Synthesis Based on Synthetic Drugs

Exercises in Organic Synthesis Based on Synthetic Drugs

Exercises in Organic Synthesis Based on Synthetic Drugs presents information on topics about the synthesis of biologically active compounds which are used against a range of diseases in both humans ...
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Hydrazine and its Derivatives

Pp. 133-149 (17)

Marcus Vinícius Nora de Souza

Abstract

The chemical hydrazine (NH2NH2) and its derivatives have several applications being also responsible for a large number of chemical transformations. This class has applications as rocket fuel and being present in the composition of explosives, in the control of corrosion, and the area of polymers. They also have full use in the development of bioactive substances being of great importance in medicinal chemistry. In the exercises of this chapter, we can synthesize several rings using hydrazine and its derivatives, and it is up to the readers to identify them.

Keywords:

Bioactive compounds, Chemical transformations, Drugs, Exercises, Heteroaromatic compounds, Hydrazine, Medicinal chemistry, Molecules, Reaction conditions, Reagents, Retrosynthetic analysis, Substances, Synthesis, Synthons.

Affiliation:

FioCruz-Fundação Oswaldo Cruz Rio de Janeiro - RJ, 21040-900, Brazil.