Abstract
Objective: Coronavirus Disease-2019 (COVID-19) is a pandemic outbreak in the world and is the leading cause of Severe Acute Respiratory Syndrome (SARS).
Methods: Currently, many drugs/therapies have been tested for COVID-19, which responded sub- -optimally to the patients. Remdesivir is an RNA polymerase inhibitor that found promising results in ongoing clinical trials and shows a faster recovery rate in COVID-19 patients. Currently, USFDA approves for emergent use of this drug in severe COVID-19 patients. Results: In this review, we discussed a brief overview of biopharmaceutical and pharmacological aspects of Remdesivir. Moreover, the ongoing regulatory status of Remdesivir by official bodies has also been described.Keywords: Remdesivir, COVID-19, USFDA, SARS, WHO, RNA polymerase inhibitor.
Coronaviruses
Title:Remdesivir, A Potential Drug for COVID-19 Treatment: A New Hope
Volume: 2 Issue: 8
Author(s): Kuldeep Singh, Dilpreet Singh* Karan Razdan
Affiliation:
- Department of Pharmaceutics, ISF College of Pharmacy, Punjab,India
Keywords: Remdesivir, COVID-19, USFDA, SARS, WHO, RNA polymerase inhibitor.
Abstract: Objective: Coronavirus Disease-2019 (COVID-19) is a pandemic outbreak in the world and is the leading cause of Severe Acute Respiratory Syndrome (SARS).
Methods: Currently, many drugs/therapies have been tested for COVID-19, which responded sub- -optimally to the patients. Remdesivir is an RNA polymerase inhibitor that found promising results in ongoing clinical trials and shows a faster recovery rate in COVID-19 patients. Currently, USFDA approves for emergent use of this drug in severe COVID-19 patients. Results: In this review, we discussed a brief overview of biopharmaceutical and pharmacological aspects of Remdesivir. Moreover, the ongoing regulatory status of Remdesivir by official bodies has also been described.Export Options
About this article
Cite this article as:
Singh Kuldeep , Singh Dilpreet *, Razdan Karan , Remdesivir, A Potential Drug for COVID-19 Treatment: A New Hope, Coronaviruses 2021; 2 (8) : e260721189256 . https://dx.doi.org/10.2174/2666796701999201218141652
DOI https://dx.doi.org/10.2174/2666796701999201218141652 |
Print ISSN 2666-7967 |
Publisher Name Bentham Science Publisher |
Online ISSN 2666-7975 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Counter-Regulatory Renin-Angiotensin System: An Important Line of
Research to Understand and Limit the Severity of COVID-19
Infectious Disorders - Drug Targets Thalidomide: An Overview of its Pharmacological Mechanisms of Action
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 3D Pharmacophore Based Virtual Screening of A2A Adenosine Receptor Antagonists
Protein & Peptide Letters Pharmacological Cyclin-Dependent Kinase Inhibitors (PCIs) as Potential Antiviral Drugs
Anti-Infective Agents in Medicinal Chemistry Molecular Targets of the Nitrogen Containing Bisphosphonates: The Molecular Pharmacology of Prenyl Synthase Inhibition
Current Pharmaceutical Design An Overview of the Current and Novel Drugs for Alzheimers Disease with Particular Reference to Anti-Cholinesterase Compounds
Current Pharmaceutical Design Synthesis and SAR of Some New 4 Substituted 3H-1,2,3,5-oxathiadiazole 2-Oxides as Antifungal Agents
Letters in Drug Design & Discovery The Activation of Procarcinogens by CYP1A1/1B1 and Related Chemo-Preventive Agents: A Review
Current Cancer Drug Targets Computational Investigation of Ligand Binding of Flavonoids in Cytochrome P450 Receptors
Current Pharmaceutical Design New and Under Explored Epigenetic Modulators in Search of New Paradigms
Medicinal Chemistry Acridones As Antiviral Agents: Synthesis, Chemical and Biological Properties
Current Medicinal Chemistry Community-Acquired Pneumonia in Children
Recent Patents on Inflammation & Allergy Drug Discovery Microbes, Immunity and Multiple Sclerosis
Current Immunology Reviews (Discontinued) Recent Advances in QSAR-based Identification and Design of Anti-Tubercular Agents
Current Pharmaceutical Design CFTR Inhibitors
Current Pharmaceutical Design Targeting the Renin-angiotensin System: Whats New?
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Dengue Patients Treated with Doxycycline Showed Lower Mortality Associated to a Reduction in IL-6 and TNF Levels
Recent Patents on Anti-Infective Drug Discovery Technological, Biochemical and Microbiological Evaluation of Dehydrated <i>Pleurotus ostreatus</i> Powder for Nutraceutical Applications
Current Nutrition & Food Science Identification of Four Urea Adducts of Andrographolide in Humans
Drug Metabolism Letters Glucocorticoid Receptors and Bone
Current Pharmaceutical Design