Heterocyclic compounds containing the quinoline ring play a significant role in organic synthesis and
therapeutic chemistry. Polyfunctionalized quinolines have attracted the attention of many research groups, especially
those who work on drug discovery and development. These derivatives have been widely explored by the
research biochemists and are reported to possess wide biological activities. This review focuses on the recent
progress in the synthesis of heterocyclic compounds based-quinoline and their potential biological activities.
Keywords: Quinoline derivatives, synthesis, biological activity, heterocyclic compounds, therapeutic chemistry, SARS-CoV-2.
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