Current Pharmaceutical Aspects of Synthetic Quinoline Derivatives

Author(s): Rukhsana Tabassum*, Muhammad Ashfaq*, Hiroyuki Oku

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 21 , Issue 10 , 2021


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Abstract:

Quinoline derivatives are considered broad-spectrum pharmacological compounds that exhibit a wide range of biological activities. Integration of quinoline moiety can improve its physical and chemical properties and also pharmacological behavior. Due to its wide range of pharmaceutical applications, it is a very popular compound to design new drugs for the treatment of multiple diseases like cancer, dengue fever, malaria, tuberculosis, fungal infections, AIDS, Alzheimer’s disease and diabetes. In this review, our major focus is to pay attention to the biological activities of quinoline compounds in the treatment of these diseases such as anti-viral, anti-cancer, anti-malarial, antibacterial, anti-fungal, anti-tubercular and anti-diabetic.

Keywords: Quinoline derivatives, heterocyclic, biologically active, pharmaceutical, broad spectrum, inhibition.

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Article Details

VOLUME: 21
ISSUE: 10
Year: 2021
Published on: 19 May, 2021
Page: [1152 - 1172]
Pages: 21
DOI: 10.2174/1389557520999201214234735
Price: $65

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