New Approaches for Hydrogen Therapy of Various Diseases

Author(s): Lei Zhang, Han Yu, Qiufen Tu, Qianjun He*, Nan Huang*

Journal Name: Current Pharmaceutical Design

Volume 27 , Issue 5 , 2021


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Abstract:

Hydrogen therapy has recently received increasing attention as an emerging and promising therapeutic technology due to its selective antioxidant property and cell energy regulatory capability in vivo. To solve the low solubility issue of hydrogen, a variety of nanomaterials and devices for hydrogen supply have recently been developed, aiming to increase the concentration of hydrogen in the specific disease site and realize controlled hydrogen release and combined treatment. In this review, we mainly focus on the latest advances in using hydrogen-generating devices and nanomaterials for hydrogen therapy. These developments include sustained release of H2, controlled release of H2, versatile modalities of synergistic therapy, etc. Also, bio-safety issues and challenges are discussed to further promote the clinical applications of hydrogen therapy and the development of hydrogen medicine.

Keywords: Hydrogen medicine, anti-inflammation, nanomaterials, devices, anti-oxidation, COVID-19.

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Article Details

VOLUME: 27
ISSUE: 5
Year: 2021
Published on: 13 March, 2021
Page: [636 - 649]
Pages: 14
DOI: 10.2174/1381612826666201211114141
Price: $65

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