Background: Shoulder-hand syndrome (SHS) refers to a syndrome causing sudden
edema, shoulder pain and limited hand function. Qingpeng ointment, a kind of Tibetan medicine,
can reduce swelling, relieve pain, tonify stagnation and clear the meridians, which is consistent
with the pathological mechanism of SHS after stroke. Therefore, if clinical trials can be used to
explore the effectiveness of Qingpeng ointment for the treatment of poststroke SHS and promote
its application in clinical medicine, it may prove the specific significance for the treatment of
poststroke SHS poststroke SHS.
Objective: The aim of the study was to investigate the clinical efficacy and safety of Qingpeng
ointment in the treatment of poststroke SHS and to provide an objective basis for a better
therapeutic treatment for poststroke SHS.
Methods: A prospective, randomized, controlled study was conducted. This study recruited 120
patients with poststroke SHS who met the inclusion criteria. They were randomized into the treatment
group and the control group, with 60 patients allocated to each group. The treatment group received
routine medical treatment and rehabilitative care after using the Qingpeng ointment, while the patients
in the control group received only routine treatment without the ointment. All patients received
clinical assessment with the Visual Analogue Scale (VAS), measurement of the range of motion
(ROM) of the upper-limb joints, the Fugl-Meyer Assessment of Upper Extremity (FMA-U) and the
Modified Barthel Index Score (MBI) before and after the whole treatment.
Results: After 4 weeks of treatment, the VAS scores of both the groups decreased significantly (P
＜0.05), and the difference between the two groups was statistically significant (P < 0.05). No
statistical significance was observed for the difference between the treatment group and control
group in terms of the FMA-U and MBI scores and the forward bend, backward, outstretch, external
rotation and pronation angles after treatment. The increases in the values of VAS, FMA-M and
MBI in the treatment group were greater than those in the control group, and the difference was
statistically significant (P < 0.05). The increases in the values of the forward bend, outreach and
external rotation angles in the treatment group were greater than those in the control group, and the
difference was statistically significant (P < 0.05).
Conclusion: The treatment group showed better results than the control group in terms of the relief
of pain symptoms, the improvement of motor function and the improvement of the activities of
daily living for patients with shoulder-hand syndrome after cerebral hemorrhage. Qingpeng
ointment was found to be effective and safe for treating poststroke SHS.