COVID-19: How Nuclear Medicine Can Provide A Differential Diagnosis In A Very Dubious Case

(E-pub Ahead of Print)

Author(s): Maria Silvia De Feo, Viviana Frantellizzi*, Giuseppe De Vincentis

Journal Name: Coronaviruses
The World's First International Journal Dedicated to Coronaviruses

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Background: We present the case of a 55-year-old woman, admitted to the Infectious Disease Department of Policlinico Umberto I, Rome, in mid-March 2020, with suspicion of COVID-19 infection.

Objective: The rRT-PCR was negative and the following CT scan, performed to exclude false-negative results and help diagnosis, was inconclusive.

Methods: It was decided to submit the patient to 99mTc-HMPAO-labelled leukocyte scan.

Results: This exam led to the diagnosis of infective endocarditis.

Conclusion: In the present pandemic scenario, 99mTc-HMPAO-labelled leukocyte scan represents a reliable imaging technique for differential diagnosis with COVID-19 in patients with confusing clinical signs, possible false-negative rRT-PCR results and inconclusive CT scan.

Keywords: COVID-19, SARS-CoV-2, 99mTc-HMPAO-labelled leukocyte, differential diagnosis, FUO.

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2666796701999201209142919