Objective: Euphorbia is a plant from the Euphorbiaceae family, and it has traditionally
been used to treat gonorrheal, respiratory tract infections, skin infections and malaria. The aim of
the present study was to evaluate antibacterial, antifungal and antioxidant activities of latex and extracts
of Euphorbia monostyla.
Materials and Methods: Antimicrobial activity was studied by Disc-well diffusion and MIC-MBC
methods.Also, its antioxidant activity was evaluated by DPPH and FRAP methods. Total phenolic
content was evaluated by Folin-Ciocalteu reagent.
Results: It is displayed as a result of the work that solvent polarity will play a key role in increasing
phenolic solubility. Methanol extract gave the highest percentage yield, and ethyl acetate resulted
in the lowest percentage yield. The antimicrobial test showed that whole extracts had no beneficial
uses on microorganisms in comparison to antibiotics types. Analysis of antioxidant assays revealed
that aqueous and methanol extracts had the highest antioxidant properties.
Conclusion: Whole extracts had no beneficial uses on microorganisms compared to antibiotics
types, but the aqueous extract of E. monostyla had moderate antioxidant activity and may contain
valuable active compounds. This work is the first study that discusses E. monostyla, and further
study is suggested to isolate its active compounds.