A coronavirus is a group of nonsegmented, single-stranded, enveloped viruses having positive RNA genomes.
This virus was first described in 1931 and the first coronavirus was isolated (HCoV-229E) from humans in 1965. People become infected with four human coronavirus strains: 229E, NL63, OC43, and HKU1 which cause respiratory associated
problems such as SARS and MERS. Lately, a new version of a strain called SARD-CoV-2 has been found. WHO called it
novel coronavirus–infected pneumonia (NCIP) and later officially renamed as COVID-19 on 11th Feb 2020. The outbreak
began in Wuhan, Hubei, China in Dec 2019 and from now the outbreak becomes pandemic. Here, we have reviewed various
categories of therapeutics, vaccines, and clinically investigated drugs to treat and prevent nCOVID-19. Till now no specific
FDA approved drugs or vaccines are available against nCOVID-19. Several options can be visualized to control or prevent
emerging infections, including antivirals, immunomodulators, interferons, vaccines, monoclonal antibodies, and biomolecules. Given the urgency of the outbreak, we have discussed some potential existing therapeutics for treating