A Closer Look to Polyesters: Properties, Synthesis, Characterization, and Particle Drug Delivery Applications

Author(s): Katherine Pazmiño Viteri*, Karla Sofía Vizuete, Frank Alexis, Brajesh Kumar, Alexis Debut

Journal Name: Nanoscience & Nanotechnology-Asia

Volume 11 , Issue 5 , 2021

Article ID: e241120188332
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Graphical Abstract:


Background: Natural and synthetic polymeric materials can be used in the fields of biomedicine and pharmaceuticals as a material for controlled drug delivery. Among the synthetic polymers, polyesters are synthesized from two natural monomers: lactic and glycolic acid, which are biocompatible and biodegradable.

Objective: Here, we review broad aspects of polyesters including its properties, synthesis, characterization, and particle drug delivery applications.

Conclusion: Finally, we have concluded that polyesters are certainly very versatile material that are continuously reinvented for future application in new areas of science and medicine. However, several aspects must be considered when synthesizing polyesters, which have a direct influence on biodegradability and biocompatibility. These properties may limit the performance of in vitro and in vivo tests.

Keywords: Polyesters, polymers, biodegradable, nanoparticles, microparticles, drug delivery.

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Article Details

Year: 2021
Published on: 24 November, 2020
Article ID: e241120188332
Pages: 35
DOI: 10.2174/2210681210999201124155313
Price: $25

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PDF: 137