Current Development in drug delivery system has been employed with an endeavour to enhance
the bioavailability of the drug, mask its taste, induce the rapid onset of action and improve patient
compliance. An alternative approach to the conventional dosage form is being employed to triumph
over all these issues named as Orodispersible system. Over the past three decades, this novel
dosage form has gained considerable attention as compared to other conventional solid dosage forms
such as tablets and capsules. ODTs dissolve or disintegrate within a few seconds or a minute when put
on the tongue, without the need for water. ODT has an advantageous effect on paediatrics and geriatrics
patients with dysphagia. Over the last decade, widespread advances in the formulation of ODTs
have been executed in academia and industry that resulted in the emergence of a large number of patents.
Products developed from ODT mechanics launched in the market in the 1980s have grown bit
by bit in demand and their products are rapidly escalating. Expanding in the technology forum based
on industrialization, these systems include the use of lyophilization, cotton candy, sublimation, melt
extrusion and direct compression in addition to the conventional wet granulation processes and patent
techniques. The present study focused on non-patent and patent citations concerning ODT along with
active ingredients, techniques used and results of the innovations.