Hydrogel: A Promising Material in Pharmaceutics

Author(s): Waseeq Ur Rehman, Muhammad Asim, Shah Hussain, Shahid Ali Khan*, Sher Bahadar Khan*

Journal Name: Current Pharmaceutical Design

Volume 26 , Issue 45 , 2020


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Abstract:

Hydrogels are natural or synthetic polymeric networks, insoluble in water, or sometimes found as colloidal gel where the dispersion medium is water. Hydrogels can absorb approximately 90% water and are regarded as superabsorbent materials; hence these resemble the natural living tissues more than any other biological- based materials. Because of their ability to absorb water, they are used to investigate the properties of swollen polymer networks and have wide applications in different fields such as contact lenses, drug delivery systems for proteins, and many others. To make them biodegradable, labile chemical bonds are introduced in the main backbone through crosslinking. These unstable bonds can then be broken down by various agents chemically, physically, or enzymatically, generally by hydrolysis or through some controlled parameters. Hydrogels are frequently used in the medical field. For instance, pH and temperature-sensitive hydrogels may be used in the targeted drug delivery which have been explained in detail in the current review. The other applications of hydrogels are also explained with regard to personal health care products, biomedical, bio-separation, wound healing, tissue engineering, and drug delivery, etc., which make them promising materials in pharmaceutics. They are also used in agriculture and environmental remediation. The purpose of this review is to expose their salient features and biomedical applications.

Keywords: Hydrogel, biomedical application, wound healing, drug delivery, personal hygiene, pets’ hygiene, contact lenses, bone tissue engineering, pharmaceutics.

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Article Details

VOLUME: 26
ISSUE: 45
Year: 2020
Published on: 24 December, 2020
Page: [5892 - 5908]
Pages: 17
DOI: 10.2174/1381612826666201118095523
Price: $65

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