The Clinical Overview of Turmeric, Turmericbased Medicines, and Turmeric Isolates
Pp. 75-112 (38)
Elin Y. Sukandar and Dhyan K. Ayuningtyas
Turmeric (Curcuma longa Linn), which belongs to the Zingiberaceae
family, is one of the most well-known and thoroughly studied medicinal plants, and is
also one of the few medicinal plants that have been scientifically proven to be
beneficial to human health. The most frequently used part of turmeric is the rhizome,
for which several studies have reported to contain high levels of beneficial essential
oils and numerous chemical constituents. One of the most well-studied chemical
constituents of turmeric is curcumin, which has exhibited the ability to target multiple
signaling pathways while also demonstrating certain pharmacological activities at the
cellular level in preclinical studies. Advancing these preclinical studies, numerous
clinical studies on various diseases involving turmeric-based medication have been
conducted, including dyspepsia, irritable bowel syndrome, peptic ulcer, and cancer
lesions, among various other diseases. We report an extensive examination of the
clinical aspect of turmeric and turmeric-based medication, including its isolates. This
review provides a comprehensive overview of the state-of-the-art clinical studies
involving turmeric and its effects on various diseases.
Curcumin, Curcuma longa, Clinical Studies, Formulation, Herbal
Medicine, Turmeric, Zingiberaceae.
Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, Bandung, Indonesia.