A Review of Research Progress on Agathis dammara and its Application Prospects for Cardiovascular Diseases and Fatty Liver Disease

Author(s): Anyi Wang, Shanshan Yue, Ankang Peng, Rong Qi*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 21 , Issue 6 , 2021


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Abstract:

Cardiovascular diseases and fatty liver disease have become the leading causes of death in modern society. However, the currently existing drugs do not solve all issues related to these diseases; thus, it is expected that more potential drugs for clinical use will be developed. Undeniably, natural products have attracted increasing attention. It is of great significance to identify effective active monomer components for drug discovery and disease prevention. As a pure natural product, Agathis dammara (AD) has antioxidant, hypolipidemic, hypoglycemic, antitumor, and anti-inflammatory activities. However, at present, there are few reports regarding the effects of AD on chronic inflammatory cardiovascular diseases, such as aneurysm, atherosclerosis, myocardial ischemia-reperfusion injury, and cardiac hypertrophy and liver diseases such as fatty liver disease. AD and products derived from it have a very broad application prospect for cardiovascular diseases and fatty liver disease.

Keywords: Agathis dammara, application prospects, cardiovascular diseases, fatty liver disease.

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Article Details

VOLUME: 21
ISSUE: 6
Year: 2021
Published on: 16 November, 2020
Page: [670 - 676]
Pages: 7
DOI: 10.2174/1389557520666201117110834
Price: $65

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