A significant percentage of costs in pharmaceutical markets is devoted to supplements, due to the confidence of
consumers on the beneficial effects of these products. Magnesium is one of the supplements with enduring and increasing
popularity. According to what is reported online this metal ion can cure, or prevent, almost all kind of diseases. This review
aims at illustrating a series of scientifically demonstrated cases in which magnesium was used in clinical practice. Except for
its ordinary use as antacid and laxative, other ascertained uses, reported in scientific literature, consist in helping to treat
several diseases such as: nocturnal leg cramps, pre-eclampsia, diabetes, depression, Parkinson’s and Alzheimer’s disease,
hypertension, some types of arrhythmias, asthma, migraine headaches, epilepsy, cerebral haemorrhage, stroke.
However, many of these promising uses of magnesium require further studies to define, the involved molecular mechanisms
which should help establishing its uses in relation to the prolonged use of supplements.