Traditional Chinese Medicine Network Pharmacology in Cardiovascular Precision Medicine

Author(s): Li Gao*, Min Cao, Jia-qi Li, Xue-mei Qin, Jiansong Fang*

Journal Name: Current Pharmaceutical Design

Volume 27 , Issue 26 , 2021


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Abstract:

Cardiovascular disease is a major disease affecting human health, and its pathogenesis is caused by many factors. Through the use of "omics" technology, precision medicine is playing an increasingly important role in the prevention and treatment of cardiovascular diseases. Dialectical treatment with traditional Chinese medicine (TCM will result in personalized treatment, which is consistent with precision medicine to a certain extent. However, due to the multitarget, multipath, and multistep characteristics of TCM, its mechanism of action is not easy to elucidate. Network pharmacology can be used to predict the mechanism, toxicity and metabolic characteristics of TCM. This review summarizes commonly used bioinformatics resources for cardiovascular diseases and TCM, as well as the opportunities and challenges of TCM in cardiovascular precision medicine, with special emphasis on network pharmacology methods.

Keywords: Cardiovascular disease, omics, traditional Chinese medicine, precision medicine, network pharmacology, transcriptome, metabolomics.

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Article Details

VOLUME: 27
ISSUE: 26
Year: 2021
Published on: 12 November, 2020
Page: [2925 - 2933]
Pages: 9
DOI: 10.2174/1381612826666201112142408
Price: $65

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