Phyto-Phospholipid Complexation as a Novel Drug Delivery System for Management of Cancer with Better Bioavailability: Current Perspectives and Future Prospects

Author(s): Ram K. Sahu*, Wael M. Aboulthana, Dinesh K. Mehta

Journal Name: Anti-Cancer Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Volume 21 , Issue 11 , 2021


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Abstract:

Cancer is the foremost cause of death, and it supports the need for the identification of novel anticancer drugs to improve the efficacy of current-therapy. While the synthetic anticancer drug is associated with numerous side effects. Hence the plant active or phytoconstituents are in high demand for the treatment of cancer due to minimum side effects. But the polar nature of phytoconstituents hindered the absorption of the drug and lowered the therapeutic efficacy. The plant activity incorporated into Phyto-phospholipid Complexation can enhance bioavailability and improved therapeutic efficacy. In this review article, advantages, limitation and application of Phyto-phospholipid complexes have been illustrated. The article highlights the application of Phyto-phospholipid complexes as a promising drug carrier system to treat cancer.

Keywords: Phyto-phospholipid complexes, cancer, bioavailability, plant active, application, limitation.

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Article Details

VOLUME: 21
ISSUE: 11
Year: 2021
Published on: 10 November, 2020
Page: [1403 - 1412]
Pages: 10
DOI: 10.2174/1871520620999201110191741
Price: $65

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