Ag(I)-promoted Decarboxylative Annulation of α-oxocarboxylic Acids with (E)-3-(2-aminophenyl)-1-phenylprop-2-en-1-ones Toward 3,4- Functionalized Quinolines

Author(s): Xiaodong Fan, Chang Wang, Jiang Cheng*

Journal Name: Letters in Organic Chemistry

Volume 18 , Issue 10 , 2021


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Abstract:

An efficient Ag-promoted decarboxylative cyclization of α-oxocarboxylic acids with (E)-3- (2-aminophenyl)-1-phenylprop-2-en-1-ones has been developed to afford a series of functionalized quinolines in moderate to good yields. This method was compatible with a variety of functional groups and provided an attractive method toward phenyl(2-phenylquinolin-3-yl)methanones.

Keywords: α-oxocarboxylic acids, (E)-3-(2-aminophenyl)-1-phenylprop-2-en-1-ones, Ag-promoted, decarboxylative cyclization, intramolecular 6π-electrocyclization, quinolines derivatives.

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Article Details

VOLUME: 18
ISSUE: 10
Year: 2021
Published on: 06 November, 2020
Page: [777 - 782]
Pages: 6
DOI: 10.2174/1570178617999201106141315
Price: $95

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