Quinone-Based Drugs: An Important Class of Molecules in Medicinal Chemistry

Author(s): Vitor F. Ferreira*, Alcione S. de Carvalho, Patricia G. Ferreira, Carolina G. S. Lima, Fernando de C. da Silva

Journal Name: Medicinal Chemistry

Volume 17 , Issue 10 , 2021


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Abstract:

Background: Several quinones are on the pharmaceutical market as drugs for the treatment of several diseases.

Objective: The aim of this review was to provide an overview of the quinones that have become drugs for several therapeutic applications.

Methods: We have comprehensively and critically discussed all the information available in the literature about quinone-based drugs.

Results: In this review, the various aspects of the chemistry and biochemistry of these drugs are highlighted, including their repositioning, drug combination and their new uses.

Conclusion: A number of studies related to quinone drugs for different pharmaceutical uses show that the interest in new applications is still increasing in recent years.

Keywords: Atovaquone, buparvaquone, parvaquone, mitomycins, doxorubicin, valrubicin, mitoxantrone.

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Article Details

VOLUME: 17
ISSUE: 10
Year: 2021
Page: [1073 - 1085]
Pages: 13
DOI: 10.2174/1573406416666201106104756
Price: $95

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