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Current Organic Synthesis

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Letter Article

Sonication Assisted One-Pot Synthesis of Substituted Imidazopyridine from Styrene in Water

Author(s): Sanjay Subhas Gaikwad, Nitin Madhu Thorat and Limbraj Rajaram Patil*

Volume 18, Issue 4, 2021

Published on: 05 November, 2020

Page: [366 - 370] Pages: 5

DOI: 10.2174/1570179417999201105160447

Price: $65

Abstract

The present protocol is a simple and eco-friendly approach for the one-pot procedure for the synthesis of substituted imidazopyridines ranging from important feedstock’s like styrene promoted by NBS. Through sonicator and microwave commercially available styrene with NBS in water followed by reaction with 2- aminopyridines afforded important heterocyclic scaffolds in an one-pot procedure.

Keywords: One-pot synthesis, imidazopyridines, microwave condition, sonication condition, green synthesis, NBS.

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