Background: COVID-19 caused by the novel SARS Coronavirus-2 (SARS-CoV-2) is causing
serious problems in the global public health sphere. In the absence of a powerful antiviral treatment,
the exploration of plant-based products with antiviral potential has gained interest.
Scope and Approach: This commentary presents the prospects of utilizing coconut oil directly or its
derivatives such as monolaurin in treating COVID-19 with a special emphasis on their biochemical
characteristics features. The potential pitfalls therein and way forward are also highlighted.
Key findings and conclusions: There are enough research-backed evidences to demonstrate the antiviral
capabilities of coconut oil and monolaurin. The possibility of developing a medium-chain fatty acidbased
nasal spray as a prophylactic or therapeutic is also discussed. Nevertheless, the potential impediments
in devising suitable therapeutic models to treat SARS-CoV-2, are presented.