Coronavirus disease 2019 (COVID-19) first emerged in a group of patients who presented
with severe pneumonia in Wuhan, China, in December 2019. A novel virus, now called SARSCoV-
2 (Severe Acute Respiratory Syndrome Coronavirus-2), was isolated from lower respiratory
tract samples. The current outbreak of infection has spread to over 100 countries and killed more
than 340,000 people as of 25th May, 2020.
The predominant clinical manifestation of COVID-19 is a respiratory disease- ranging from mild
flu-like symptoms to fulminant pneumonia and Acute Respiratory Distress Syndrome (ARDS). Patients
with pre-existing cardiovascular risk factors are considered more susceptible to the virus, and
these conditions are often worsened by the infection. Furthermore, COVID-19 infection has led to
de novo cardiac complications, like acute myocardial injury and arrhythmias.
In this review, we have focused on the cardiovascular manifestations of COVID-19 infection that
have been reported in the literature so far. We have also outlined the effect of pre-existing cardiovascular
disease as well as risk factors on the clinical course and outcomes of COVID-19 infection.