Tissue engineering is governed by the use of cells and polymers. The cells may be accounted
for the type of tissue to be targeted, while polymers may vary from natural to synthetic.
The natural polymers have advantages such as non-immunogenic and complex structures that help
in the formation of bonds in comparison to the synthetic ones. Various targeted drug delivery systems
have been prepared using polymers and cells, such as nanoparticles, hydrogels, nanofibers,
and microspheres. The design of scaffolds depends on the negative impact of material used on the
human body and they have been prepared using surface modification technique or neo material synthesis.
The dermal substitutes are a distinctive array that aims at the replacement of skin parts either
through grafting or some other means. This review focuses on biomaterials for their use in tissue
engineering. This article shall provide the bird's eye view of the scaffolds and dermal substitutes,
which are naturally derived.
Keywords: Scaffolds, dermal substitutes, tissue engineering, hydrogels, natural polymers, nanofibers.
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