Perspectives for the Use of N-acetylcysteine as a Candidate Drug to Treat COVID-19

Author(s): Pan Luo, Yi Liu, Dong Liu*, Juan Li*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 21 , Issue 3 , 2021


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Abstract:

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndromerelated coronavirus-2 (SARS-CoV-2), has become an ongoing pandemic worldwide. However, there are no vaccines or antiviral drugs with proven clinical efficacy. Therefore, a remedial measure is urgently needed to combat the devastating COVID-19. The pharmacological activities of Nacetylcysteine (NAC) and its potential functions in inhibiting the progression of COVID-19 make it a promising therapeutic agent for the infection. In this mini-review, we discussed the therapeutic potential of NAC in COVID-19 from the perspective of its multisite pharmacological actions.

Keywords: COVID-19, SARS-COV-2, N-acetylcysteine, oxidative stress, inflammation, thrombosis, nitric oxide, mental disorders.

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Article Details

VOLUME: 21
ISSUE: 3
Year: 2021
Published on: 11 February, 2021
Page: [268 - 272]
Pages: 5
DOI: 10.2174/1389557520666201027160833

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