Natural and Nanotechnology Based Treatment: An Alternative Approach to Psoriasis

Author(s): Nishu Yadav*, Rohan Aggarwal, Monika Targhotra, Prabhat K. Sahoo, Meenakshi K. Chauhan

Journal Name: Current Nanomedicine
(Formerly Recent Patents on Nanomedicine)

Volume 11 , Issue 1 , 2021


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Graphical Abstract:


Abstract:

Psoriasis is an autoimmune disease of the skin that is chronic, inflammatory, recurring, and affects about 2-5 percent of the population of the world. For treating psoriasis, ample drugs and molecules are available. However, none are safe and efficient for treating the disease without sacrificing the compliance of the patient. Also, existing medications are intended to mitigate the signs and symptoms and 100% cure is not achieved. They do, however, concentrate on treating the illness and relieving the symptoms. Therefore, finding a delivery mechanism that can treat psoriasis safely and efficiently without sacrificing patient enforcement remains a critical task. Nano based formulations present a high prospect of overcoming the weakness of traditional formulations by providing dose reductions, reduced side effects, and dosage frequency with improved efficacy while herbal medicinal products can also be used as potential drugs against psoriasis as they are easily available and are safe. This review focuses primarily on the traditional strategies and recent discoveries of a range of anti-psoriatic drugs in metallic, polymer, and herbal-based formulations. Nanocarriers such as nanoparticles, dendrimers, micelles, nano-capsules, solid lipid nanoparticles (SLN), ethosome, liposomes have been elaborated. Also, studies relating to the use of Phyto based plants in psoriasis has been discussed. Nano and herbal based formulations, in a nutshell, remain known as a promising approach for treating psoriasis.

Keywords: Psoriasis, conventional therapies, nanotechnology, herbal treatment, nanocarriers, autoimmune disease.

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