Psoriasis is an autoimmune disease of the skin that is chronic, inflammatory, recurring,
and affects about 2-5 percent of the population of the world. For treating psoriasis, ample drugs
and molecules are available. However, none are safe and efficient for treating the disease without
sacrificing the compliance of the patient. Also, existing medications are intended to mitigate the
signs and symptoms and 100% cure is not achieved. They do, however, concentrate on treating the
illness and relieving the symptoms. Therefore, finding a delivery mechanism that can treat psoriasis
safely and efficiently without sacrificing patient enforcement remains a critical task. Nano
based formulations present a high prospect of overcoming the weakness of traditional formulations
by providing dose reductions, reduced side effects, and dosage frequency with improved efficacy
while herbal medicinal products can also be used as potential drugs against psoriasis as they are easily
available and are safe. This review focuses primarily on the traditional strategies and recent discoveries
of a range of anti-psoriatic drugs in metallic, polymer, and herbal-based formulations.
Nanocarriers such as nanoparticles, dendrimers, micelles, nano-capsules, solid lipid nanoparticles
(SLN), ethosome, liposomes have been elaborated. Also, studies relating to the use of Phyto based
plants in psoriasis has been discussed. Nano and herbal based formulations, in a nutshell, remain
known as a promising approach for treating psoriasis.