Title:Research and Patents on Coronavirus and COVID-19: A Review
VOLUME: 14 ISSUE: 4
Author(s):Pilar Aranda, Bernd Wicklein, Cristina Ruiz-Garcia, Raquel Martín-Sampedro, Margarita Darder, Gustavo del Real and Eduardo Ruiz-Hitzky*
Affiliation:Materials Science Institute of Madrid, ICMM-CSIC, c/Sor Juana Ines de la Cruz 3, 28049, Madrid, Materials Science Institute of Madrid, ICMM-CSIC, c/Sor Juana Ines de la Cruz 3, 28049, Madrid, Centre National de la Recherche Scientifique, CNRS, CEMHTI, (UPR 3079), Universite d’Orleans, 45071 Orleans, Materials Science Institute of Madrid, ICMM-CSIC, c/Sor Juana Ines de la Cruz 3, 28049, Madrid, Materials Science Institute of Madrid, ICMM-CSIC, c/Sor Juana Ines de la Cruz 3, 28049, Madrid, National Institute of Agricultural and Food Research, INIA, Ctra de la Coruna Km 7.5, Madrid 28040, Materials Science Institute of Madrid, ICMM-CSIC, c/Sor Juana Ines de la Cruz 3, 28049, Madrid
Keywords:COVID-19, SARS-CoV-2, detection, prophylaxis, diagnosis, treatment, vaccines, nanoparticles.
Abstract:
Background: COVID-19 pandemic is a global problem that requires the point of view of basic
sciences and medicine as well as social, economics and politics disciplines. Viral particles of
coronaviruses including SARS-CoV-2 as well as other enveloped viruses like influenza virus could be
considered as an approximation to functional core-shell nanoparticles and therefore, their study enters
the realm of nanotechnology. In this context, nanotechnology can contribute to alleviate some of the current
challenges posed by COVID-19 pandemic.
Methods: The present analysis contributed to diverse sources of general information, databases on scientific
literature and patents to produce a review affording information on relevant areas where as
nanotechnology has offered response to coronavirus challenges in the past and may be relevant now, and
has offered an update of the current information on SARS-CoV-2 and COVID-19 issues.
Results: This review contribution includes specific information including: 1) An introduction to current research
on nanotechnology and related recent patents for COVID-19 responses; 2) Analysis of nonimmunogenic
and immunogenic prophylaxis of COVID-19 using Nanotechnology; 3) Tools devoted to detection
& diagnosis of coronaviruses and COVID-19: the role of Nanotechnology; and 4) A compilation on
the research and patents on nanotechnology dealing with therapeutics & treatments of COVID-19.
Conclusion: Among the increasing literature on COVID-19, there are few works analyzing the relevance
of Nanotechnology, and giving an analysis on patents dealing with coronaviruses that may provide
useful information on the area. This review offers a general view of the current research investigation
and recent patents dealing with aspects of immunogenic and non-immunogenic prophylaxis, detection
and diagnosis as well as therapeutics and treatments.
