Single-cell RNA Sequencing in Immunology

Author(s): Yirui Cao, Yue Qiu, Guowei Tu*, Cheng Yang*

Journal Name: Current Genomics

Volume 21 , Issue 8 , 2020


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Graphical Abstract:


Abstract:

The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions.

Keywords: Single-cell RNA sequencing, immunology, cancer, autoimmune disease, transplantation, tumors.

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VOLUME: 21
ISSUE: 8
Year: 2020
Published on: 20 October, 2020
Page: [564 - 575]
Pages: 12
DOI: 10.2174/1389202921999201020203249
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