p-Sulfonic Acid Calix[n]arene Catalyzed Synthesis of Bioactive Heterocycles: A Review

Author(s): Bubun Banerjee*, Gurpreet Kaur, Navdeep Kaur

Journal Name: Current Organic Chemistry

Volume 25 , Issue 1 , 2021

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Graphical Abstract:


Metal-free organocatalysts are becoming an important tool for the sustainable development of various bioactive heterocycles. On the other hand, during the last two decades, calix[n]arenes have been gaining considerable attention due to their wide range of applicability in the field of supramolecular chemistry. Recently, sulfonic acid functionalized calix[n] arenes are being employed as an efficient alternative catalyst for the synthesis of various bioactive scaffolds. In this review, we have summarized the catalytic efficiency of p-sulfonic acid calix[n]arenes for the synthesis of diverse, biologically promising scaffolds under various reaction conditions. There is no such review available in the literature showing the catalytic applicability of p-sulfonic acid calix[n]arenes. Therefore, it is strongly believed that this review will surely attract those researchers who are interested in this fascinating organocatalyst.

Keywords: p-Sulfonic acid calix[n]arenes, N-heterocycles, O-heterocycles, organocatalysis, bioactivity, scaffolds.

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Article Details

Year: 2021
Published on: 01 February, 2021
Page: [209 - 222]
Pages: 14
DOI: 10.2174/1385272824999201019162655

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